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• Activity deltas table
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Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.146

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_113346284	4.584	NM_002711	PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A
chrX_-_21686079	4.139	NM_014332	SMPX	small muscle protein, X-linked
chr5_-_94250357	3.872		MCTP1	multiple C2 domains, transmembrane 1
chr10_-_95231933	2.430	NM_013451 NM_133337	MYOF	myoferlin
chr17_-_36533903	2.354	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr7_-_41709191	2.264	NM_002192	INHBA	inhibin, beta A
chr3_-_102194938	2.180	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr12_+_79625538	2.068	NM_002469	MYF6	myogenic factor 6 (herculin)
chr14_-_30927931	1.903	NM_015473	HEATR5A	HEAT repeat containing 5A
chr4_+_169654742	1.862	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr6_-_123999640	1.831	NM_006073	TRDN	triadin
chr5_+_155686333	1.755	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr4_+_120276386	1.754	NM_016599	MYOZ2	myozenin 2
chr2_-_179623030	1.735	NM_173648	CCDC141	coiled-coil domain containing 141
chr2_+_102744921	1.735	NM_144632	TMEM182	transmembrane protein 182
chr3_-_57301749	1.705	NM_001142733	ASB14	ankyrin repeat and SOCS box containing 14
chr3_-_150422474	1.693	NM_000096	CP	ceruloplasmin (ferroxidase)
chr16_+_14187965	1.688		MKL2	MKL/myocardin-like 2
chr7_-_11838260	1.684	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr12_-_55931172	1.649	NM_145064	STAC3	SH3 and cysteine rich domain 3
chr2_-_165768798	1.619	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr5_-_24535386	1.580	NM_001190450	CDH10	cadherin 10, type 2 (T2-cadherin)
chr20_-_14266200	1.518	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr8_+_67201684	1.474	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr9_+_109131814	1.473		RAD23B	RAD23 homolog B (S. cerevisiae)
chr5_-_16561936	1.460	NM_019000	FAM134B	family with sequence similarity 134, member B
chr9_+_21430439	1.450	NM_024013	IFNA1	interferon, alpha 1
chr13_+_75232797	1.429	NM_015842	LMO7	LIM domain 7
chr17_-_10265991	1.413	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr15_-_68781662	1.396	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_21175394	1.383	NM_006446	SLCO1B1	solute carrier organic anion transporter family, member 1B1
chr11_+_55776251	1.378	NM_001004747	OR5T3	olfactory receptor, family 5, subfamily T, member 3
chr11_-_30910074	1.362	NM_020869	DCDC5	doublecortin domain containing 5
chr21_-_18697829	1.348	NM_002772	TMPRSS15	transmembrane protease, serine 15
chr1_+_62835759	1.347	NM_014495	ANGPTL3	angiopoietin-like 3
chr10_+_69539255	1.342	NM_032578	MYPN	myopalladin
chr5_+_140532385	1.282	NM_018940	PCDHB7	protocadherin beta 7
chr3_-_147361465	1.238		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_-_9925412	1.235	NM_032368	LZIC	leucine zipper and CTNNBIP1 domain containing
chr2_-_236837726	1.234	NM_212556	ASB18	ankyrin repeat and SOCS box containing 18
chr21_-_35174742	1.232		RUNX1	runt-related transcription factor 1
chr3_-_95230143	1.231	NM_001001850	STX19	syntaxin 19
chr20_+_56369012	1.221
chr1_-_202595666	1.206	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr3_-_193928038	1.188	NM_004113	FGF12	fibroblast growth factor 12
chr10_+_96688399	1.175	NM_000771	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
chr9_+_104797413	1.172	NM_001340	CYLC2	cylicin, basic protein of sperm head cytoskeleton 2
chr4_+_141484046	1.169	NM_001153446 NM_001153635 NM_001153585 NM_001153690	SCOC	short coiled-coil protein
chr2_-_105421661	1.161	NM_201557	FHL2	four and a half LIM domains 2
chr10_-_75085754	1.135	NM_001114133	SYNPO2L	synaptopodin 2-like
chr6_+_55300225	1.128	NM_207410	GFRAL	GDNF family receptor alpha like
chr12_+_53699995	1.126	NM_021191	NEUROD4	neurogenic differentiation 4
chr4_-_186934059	1.118	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr1_-_100416358	1.117	NM_144620	LRRC39	leucine rich repeat containing 39
chr5_+_53787187	1.100	NM_006308	HSPB3	heat shock 27kDa protein 3
chr4_-_64957595	1.097	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr1_+_15862887	1.086
chr1_-_150328153	1.063	NM_001008536	TCHHL1	trichohyalin-like 1
chr3_+_190147633	1.045		TPRG1	tumor protein p63 regulated 1
chr10_-_69125932	1.021	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr20_+_19903778	1.016		RIN2	Ras and Rab interactor 2
chr9_+_5221401	1.016	NM_002195	INSL4	insulin-like 4 (placenta)
chr2_-_215956429	1.008		FN1	fibronectin 1
chr3_+_23904086	1.002		UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr15_+_61676604	0.999	NM_203373	FBXL22	F-box and leucine-rich repeat protein 22
chrX_+_70438352	0.995	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr2_+_88148413	0.987	NM_198274	SMYD1	SET and MYND domain containing 1
chr5_-_66528330	0.984	NM_005582	CD180	CD180 molecule
chr3_+_35658852	0.978	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr12_-_109842736	0.976	NM_000432	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr3_+_139550368	0.973		MRAS	muscle RAS oncogene homolog
chr9_-_21218132	0.972	NM_021268	IFNA17	interferon, alpha 17
chr3_+_120982020	0.958	NM_003889 NM_033013	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr16_-_70591377	0.954	NM_181536	PKD1L3	polycystic kidney disease 1-like 3
chr11_-_113149602	0.950	NM_004724	ZW10	ZW10, kinetochore associated, homolog (Drosophila)
chr3_+_180853473	0.939	NM_003940	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr19_-_52427698	0.936	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr7_+_93862137	0.919		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr11_-_113149642	0.909		ZW10	ZW10, kinetochore associated, homolog (Drosophila)
chr14_-_93493519	0.905	NM_016150	ASB2	ankyrin repeat and SOCS box containing 2
chr12_+_53005183	0.903		COPZ1	coatomer protein complex, subunit zeta 1
chr19_+_20750949	0.900
chr2_+_161701711	0.896	NM_004180 NM_133484	TANK	TRAF family member-associated NFKB activator
chr3_+_51837608	0.895	NM_001085479	IQCF3	IQ motif containing F3
chr6_+_131613196	0.888	NM_004842 NM_138633	AKAP7	A kinase (PRKA) anchor protein 7
chr3_-_42818221	0.884
chr12_+_53005192	0.883		COPZ1	coatomer protein complex, subunit zeta 1
chr12_+_53005194	0.881		COPZ1	coatomer protein complex, subunit zeta 1
chr10_-_44794146	0.875	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr13_-_59223074	0.875
chr11_+_69176391	0.873		CCND1	cyclin D1
chr12_+_53005177	0.873	NM_016057	COPZ1	coatomer protein complex, subunit zeta 1
chr9_-_101621964	0.872
chr3_-_178396892	0.871		TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr8_-_23768242	0.867	NM_003155	STC1	stanniocalcin 1
chr5_+_140160966	0.858	NM_018906 NM_031497	PCDHA3	protocadherin alpha 3
chr2_+_170074457	0.853	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr2_-_64944214	0.840
chr5_+_127016605	0.837	NM_001127385	CTXN3	cortexin 3
chr7_-_83116414	0.834	NM_012431	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr18_-_3209846	0.834		MYOM1	myomesin 1, 185kDa
chr5_+_121493113	0.830	NM_207317	ZNF474	zinc finger protein 474
chr19_+_53640841	0.828	NM_031485	GRWD1	glutamate-rich WD repeat containing 1
chr2_-_189752575	0.824	NM_000393	COL5A2	collagen, type V, alpha 2
chr11_+_35922106	0.823	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr17_+_15843418	0.823	NM_017775	TTC19	tetratricopeptide repeat domain 19
chrX_-_116991728	0.823	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr3_+_139550134	0.816	NM_001085049	MRAS	muscle RAS oncogene homolog
chr8_+_27687821	0.814	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chrX_-_142549984	0.811	NM_001184750	SLITRK4	SLIT and NTRK-like family, member 4
chr18_+_3443771	0.805	NM_173211	TGIF1	TGFB-induced factor homeobox 1
chr11_-_62213577	0.804		LRRN4CL	LRRN4 C-terminal like
chr15_+_66695932	0.803	NM_001190456	CORO2B	coronin, actin binding protein, 2B
chr13_-_50315832	0.802	NM_198989	DLEU7	deleted in lymphocytic leukemia, 7
chr2_+_69055208	0.801	NM_019617	GKN1	gastrokine 1
chr8_+_128875902	0.799		PVT1	Pvt1 oncogene (non-protein coding)
chr22_-_49363711	0.796	NM_004377 NM_152246 NM_001145134 NM_001145135 NM_001145136 NM_152245	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr4_-_77163609	0.795	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr3_-_147806692	0.793	NM_001085420	PLSCR5	phospholipid scramblase family, member 5
chr5_+_175041069	0.785	NM_022304	HRH2	histamine receptor H2
chr15_+_63156206	0.784	NM_001101362	KBTBD13	kelch repeat and BTB (POZ) domain containing 13
chr11_-_62213946	0.783	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr13_-_44673174	0.777	NM_198404	KCTD4	potassium channel tetramerisation domain containing 4
chr5_-_142045770	0.776	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr6_+_53991672	0.774	NM_138569	C6orf142	chromosome 6 open reading frame 142
chr4_+_77214886	0.771	NM_001130016 NM_001179	ART3	ADP-ribosyltransferase 3
chr6_+_73133152	0.769	NM_001168411	RIMS1	regulating synaptic membrane exocytosis 1
chr10_+_86174665	0.766		FAM190B	family with sequence similarity 190, member B
chr3_-_152659186	0.763	NM_178822	IGSF10	immunoglobulin superfamily, member 10
chr10_+_50177192	0.756	NM_001135196 NM_199459	C10orf71	chromosome 10 open reading frame 71
chr12_-_8656705	0.753	NM_020661	AICDA	activation-induced cytidine deaminase
chr19_-_51856129	0.751	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr4_+_111053488	0.750	NM_001178130 NM_001178131 NM_001963	EGF	epidermal growth factor
chr22_+_40372957	0.748		XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_-_20390601	0.738	NM_015317	PUM2	pumilio homolog 2 (Drosophila)
chr18_+_74957475	0.736
chr17_+_55098280	0.736		CLTC	clathrin, heavy chain (Hc)
chr12_-_10215942	0.729	NM_001172632 NM_001172633 NM_002543	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr6_-_128281434	0.729	NM_001164687	THEMIS	thymocyte selection associated
chr10_-_127559841	0.723	NM_018180	DHX32	DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr4_-_5881271	0.714		CRMP1	collapsin response mediator protein 1
chr10_-_7701619	0.712	NM_032817	ITIH5	inter-alpha (globulin) inhibitor H5
chr2_-_162808123	0.710	NM_004460	FAP	fibroblast activation protein, alpha
chr16_+_65790514	0.705	NM_024712	ELMO3	engulfment and cell motility 3
chr10_-_75080784	0.697	NM_024875	SYNPO2L	synaptopodin 2-like
chr17_-_15914485	0.694		NCOR1	nuclear receptor corepressor 1
chr7_-_27133163	0.694	NM_153631	HOXA3	homeobox A3
chr4_+_123311207	0.688	NM_015312	KIAA1109	KIAA1109
chr16_+_31132842	0.688	NM_001008274	TRIM72	tripartite motif containing 72
chr7_+_93373755	0.685	NM_021955	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr1_-_151296611	0.683	NM_005988	SPRR2A	small proline-rich protein 2A
chr1_+_184636326	0.682	NM_022375	OCLM	oculomedin
chr9_-_21229975	0.681	NM_002172	IFNA14	interferon, alpha 14
chr1_-_148959945	0.679	NM_032132	HORMAD1	HORMA domain containing 1
chr1_+_78243181	0.678	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_-_31618405	0.674	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr12_-_68379331	0.670	NM_032735	BEST3	bestrophin 3
chr7_+_80069439	0.669	NM_001001547	CD36	CD36 molecule (thrombospondin receptor)
chr5_+_92944680	0.668	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr1_-_156923111	0.664	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_113853790	0.663	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr18_-_3209986	0.656	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr19_-_9186512	0.656	NM_001005191	OR7D4	olfactory receptor, family 7, subfamily D, member 4
chr17_+_65677255	0.655	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr18_-_49944986	0.650		MBD2	methyl-CpG binding domain protein 2
chr1_-_205012348	0.650	NM_000572	IL10	interleukin 10
chr2_+_5750229	0.644	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr5_+_70980724	0.643		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_-_36929520	0.639		STRN	striatin, calmodulin binding protein
chr5_-_137502975	0.638	NM_003551	NME5	non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr3_+_36396948	0.635	NM_003149	STAC	SH3 and cysteine rich domain
chr3_-_46224791	0.633	NM_001295	CCR1	chemokine (C-C motif) receptor 1
chr4_-_88669625	0.633	NM_001128310 NM_004684	SPARCL1	SPARC-like 1 (hevin)
chr11_+_68124400	0.631		PPP6R3	protein phosphatase 6, regulatory subunit 3
chr5_-_58688428	0.631	NM_001197219	PDE4D	phosphodiesterase 4D, cAMP-specific
chr6_-_48186868	0.630		C6orf138	chromosome 6 open reading frame 138
chr9_+_123088217	0.628		GSN	gelsolin
chr9_+_96561750	0.624	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr6_+_72979234	0.624	NM_001168407 NM_001168408	RIMS1	regulating synaptic membrane exocytosis 1
chr5_-_137876416	0.622		ETF1	eukaryotic translation termination factor 1
chr5_-_83052606	0.622	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr17_-_10500189	0.618	NM_002470	MYH3	myosin, heavy chain 3, skeletal muscle, embryonic
chr14_-_31026901	0.618	NM_001197184	GPR33	G protein-coupled receptor 33 (gene/pseudogene)
chr1_-_71319265	0.618		ZRANB2	zinc finger, RAN-binding domain containing 2
chr20_+_2224612	0.618	NM_003245	TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr8_+_76614757	0.617	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr15_+_91244422	0.615	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr6_-_2696152	0.615	NM_001012418	MYLK4	myosin light chain kinase family, member 4
chr9_+_115367122	0.615	NM_134427	RGS3	regulator of G-protein signaling 3
chr6_+_149763187	0.614	NM_001002255	SUMO4	SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr17_-_44400952	0.613	NM_004123	GIP	gastric inhibitory polypeptide
chr3_-_150533948	0.613	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr1_-_94475840	0.613	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chrX_-_138742050	0.610	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr7_-_56128098	0.609	NM_006213	PHKG1	phosphorylase kinase, gamma 1 (muscle)
chr12_-_10850845	0.605	NM_023918	TAS2R8	taste receptor, type 2, member 8
chr1_-_151333624	0.605	NM_001024209	SPRR2E	small proline-rich protein 2E
chr15_-_74941339	0.600	NM_001145923	SCAPER	S-phase cyclin A-associated protein in the ER
chr15_+_91244563	0.598		CHD2	chromodomain helicase DNA binding protein 2
chr2_+_33514896	0.597	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.42	1.92e-03	GO:0007517	muscle organ development
2.02	2.99e-02	GO:0061061	muscle structure development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.41	2.95e-07	GO:0030016	myofibril
3.32	3.31e-07	GO:0043292	contractile fiber
3.38	6.54e-07	GO:0044449	contractile fiber part
3.38	7.97e-06	GO:0030017	sarcomere

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.85	9.38e-03	GO:0008307	structural constituent of muscle
1.57	3.06e-02	GO:0005509	calcium ion binding